Across TCGA pan-cancer cohorts, MIR6829 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR6829’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR6829 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR6829 is over-expressed in tumor, although a few such as HNSC and READ show the opposite, repressed pattern.
HNSC and READ are the cancer types where MIR6829 tumor–normal differential expression is most reproducible.