MIR6821

Across TCGA patient cohorts, MIR6821 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,209 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR6821-associated GO terms across cancer lineages are Response to corticotropin-releasing hormone, Glycerophospholipid metabolic process, and Obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Each is linked with MIR6821 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIR6821-to-partner and partner-to-MIR6821 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to corticotropin-releasing hormone grouped by MIR6821-low versus MIR6821-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6821→partner) and Y-score (partner→MIR6821) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Response to corticotropin-releasing hormone →	+0.159	+0.481	.007	.001	3	9
DLBC	Glycerophospholipid metabolic process →	+0.044	+0.572	.004	.002	3	7
HNSC	Obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress →	+0.028	+0.274	<.001	<.001	3	6
LUAD	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.035	+0.287	<.001	<.001	3	6
THYM	Regulation of miRNA catabolic process →	+0.050	+0.241	.005	<.001	3	6
LUAD	ATP transport →	+0.029	+0.264	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,209 associations by consensus.

Response to corticotropin-releasing hormone by MIR6821 expression — LAML

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