Across TCGA pan-cancer cohorts, MIR6813 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR6813’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR6813 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR6813 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.
LUAD and LUSC are the cancer types where MIR6813 tumor–normal differential expression is most reproducible.