Across TCGA pan-cancer cohorts, MIR6806 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR6806’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR6806 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR6806 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
LUAD and KIRP are the cancer types where MIR6806 tumor–normal differential expression is most reproducible.