Across TCGA pan-cancer cohorts, MIR6777 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MIR6777’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MIR6777 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR6777 is over-expressed in tumor.
UCEC are the cancer types where MIR6777 tumor–normal differential expression is most reproducible.