MIR6776

Across TCGA pan-cancer cohorts, MIR6776 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MIR6776 data layer.

The strongest signal is observed in thymoma (THYM), where higher MIR6776 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR6776 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRP show a favorable association.

THYM, KICH, and COAD are the cancer types where MIR6776 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	III,IV	0.103	0.944	<.001	96	view →
KICH	DFS	Quartile	III,IV	0.053	0.821	<.001	95	view →
COAD	DFS	Tertile	All	0.419	0.559	.016	48	view →
UVM	DFS	Tertile	All	0.234	0.803	<.001	45	view →
OV	DFS	Tertile	II,III,IV	0.481	0.569	.006	42	view →
HNSC	OS	Tertile	IV	0.845	0.670	.010	39	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
KIRC	OS	Tertile	All	0.500	0.672	.011	30	view →
KIRP	OS	Tertile	All	0.944	0.857	.019	20	view →
PCPG	DFS	Tertile	All	0.510	0.861	<.001	18	view →
SKCM	OS	Tertile	IV	0.213	0.775	<.001	9	view →
SARC	OS	Tertile	All	0.491	0.785	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MIR6776–THYM (OS)

Open the THYM breakdown →