MIR6761

Across TCGA patient cohorts, MIR6761 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,368 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR6761-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Base-excision repair, AP site formation, and Establishment of protein localization to membrane. Each is linked with MIR6761 in more than 14 cancer types. Because this analysis shows association rather than direction, both MIR6761-to-partner and partner-to-MIR6761 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA processing grouped by MIR6761-low versus MIR6761-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6761→partner) and Y-score (partner→MIR6761) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of mRNA processing →	+0.043	+0.389	.007	.006	2	15
KIRP	Base-excision repair, AP site formation →	+0.040	+0.167	<.001	<.001	3	14
ESCA	Establishment of protein localization to membrane →	+0.039	+0.479	.006	<.001	2	14
ESCA	Regulation of RNA splicing →	+0.061	+0.652	<.001	<.001	3	13
STAD	Regulation of protein deubiquitination →	+0.055	+0.363	<.001	<.001	3	12
ESCA	Positive regulation of intracellular protein transport →	+0.049	+0.543	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,368 associations by consensus.

Negative regulation of mRNA processing by MIR6761 expression — ESCA

Explore this box plot interactively →