MIR6757

Across TCGA pan-cancer cohorts, MIR6757 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR6757’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR6757 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR6757 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, UCEC, and KICH are the cancer types where MIR6757 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR6757 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.950	<.001	6	view →
UCEC	All	All	−0.770	.004	4	view →
KICH	Male	IV	+1.520	<.001	3	view →
LUSC	All	All	−0.610	<.001	3	view →
KIRP	All	All	−0.529	.025	2	view →
BLCA	All	IV	−1.061	.008	1	view →
KIRC	All	All	+0.280	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MIR6757–BRCA

Open the BRCA breakdown →