MIR6754

Across TCGA patient cohorts, MIR6754 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,998 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR6754-associated GO terms across cancer lineages are Signal transduction in response to DNA damage, Glycerolipid biosynthetic process, and Regulation of protein acetylation. Each is linked with MIR6754 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR6754-to-partner and partner-to-MIR6754 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction in response to DNA damage grouped by MIR6754-low versus MIR6754-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6754→partner) and Y-score (partner→MIR6754) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Signal transduction in response to DNA damage →	+0.032	+0.048	.002	<.001	3	8
ESCA	Glycerolipid biosynthetic process →	+0.032	+0.305	.002	.005	3	7
OV	Regulation of protein acetylation →	+0.032	+0.092	<.001	.006	2	7
LAML	Negative regulation of stem cell differentiation →	+0.050	+0.744	<.001	<.001	3	6
KIRC	Regulation of peptidyl-lysine acetylation →	+0.030	+0.076	<.001	<.001	3	6
LIHC	Positive regulation of chromosome organization →	+0.037	+0.060	.008	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,998 associations by consensus.

Signal transduction in response to DNA damage by MIR6754 expression — LIHC

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