MIR6753

Across TCGA patient cohorts, MIR6753 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,135 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR6753-associated GO terms across cancer lineages are Somatic diversification of immune receptors, Lymphocyte activation involved in immune response, and Immunoglobulin production involved in immunoglobulin-mediated immune response. Each is linked with MIR6753 in more than 29 cancer types. Because this analysis shows association rather than direction, both MIR6753-to-partner and partner-to-MIR6753 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somatic diversification of immune receptors grouped by MIR6753-low versus MIR6753-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6753→partner) and Y-score (partner→MIR6753) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Somatic diversification of immune receptors →	+0.059	+1.355	<.001	<.001	3	30
DLBC	Lymphocyte activation involved in immune response →	+0.049	+1.145	.001	<.001	3	30
DLBC	Immunoglobulin production involved in immunoglobulin-mediated immune response →	+0.054	+1.499	<.001	<.001	3	30
DLBC	Vacuolar transport →	+0.068	+1.791	.001	<.001	3	30
ESCA	Cortical actin cytoskeleton organization →	+0.068	+0.710	<.001	<.001	3	29
DLBC	Positive regulation of GTPase activity →	+0.038	+1.479	.003	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

Somatic diversification of immune receptors by MIR6753 expression — DLBC

Explore this box plot interactively →