MIR6749

Across TCGA patient cohorts, MIR6749 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,729 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR6749-associated GO terms across cancer lineages are B cell mediated immunity, Cerebellar granular layer development, and Negative regulation of protein polyubiquitination. Each is linked with MIR6749 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR6749-to-partner and partner-to-MIR6749 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by MIR6749-low versus MIR6749-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6749→partner) and Y-score (partner→MIR6749) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	B cell mediated immunity →	+0.054	+0.026	.009	.001	3	2
LAML	Cerebellar granular layer development →	-0.054	-0.484	.001	<.001	3	2
BRCA	Negative regulation of protein polyubiquitination →	+0.043	+0.026	<.001	<.001	3	2
HNSC	Positive regulation of lymphocyte differentiation →	+0.056	+0.047	<.001	<.001	3	2
HNSC	Regulation of osteoclast differentiation →	+0.049	+0.038	<.001	.001	3	2
HNSC	Positive regulation of alpha-beta T cell activation →	+0.054	+0.034	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,729 associations by consensus.

B cell mediated immunity by MIR6749 expression — HNSC

Explore this box plot interactively →