MIR6746

Across TCGA pan-cancer cohorts, MIR6746 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MIR6746 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR6746 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6746 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

ACC, LUSC, and THCA are the cancer types where MIR6746 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.421	0.776	<.001	86	view →
LUSC	DFS	Tertile	II,III,IV	0.472	0.670	<.001	52	view →
THCA	OS	Quartile	IV	0.858	1.000	.009	42	view →
SKCM	OS	Tertile	All	0.866	0.759	.010	40	view →
ESCA	OS	Tertile	IV	0.135	0.568	.031	36	view →
UVM	DFS	Quartile	III,IV	0.236	0.684	.001	21	view →
LGG	DFS	Quartile	All	0.739	0.891	.001	21	view →
PRAD	DFS	Tertile	All	0.809	0.904	.005	18	view →
LIHC	DFS	Tertile	All	0.174	0.340	<.001	18	view →
BLCA	DFS	Median	IV	0.452	0.304	.028	12	view →
COAD	OS	Tertile	All	0.784	0.888	.011	12	view →
CHOL	DFS	Median	All	0.650	0.232	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MIR6746–ACC (DFS)

Open the ACC breakdown →