Q-omics provides the consensus-scored MIR653 profile across patient tissues and cancer cell-line models. MIR653 expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in LAML. Additionally, MIR653 RNA expression shows 7,667 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight LAML, and COAD as cancer lineages where MIR653 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR653 survival associations across molecular data types. MIR653 RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR653 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	LAML (36)	view →

This table ranks reproducible MIR653 RNA expression–survival associations across cancer types. High MIR653 expression shows unfavorable associations in LAML, SARC, STAD and THYM. The LAML Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LAML as the clearest survival context for MIR653 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LAML	DFS	Tertile	All	0.027	0.583	<.001	36	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →
STAD	DFS	Tertile	All	0.428	0.724	.011	27	view →
THYM	OS	Tertile	II,III,IV	0.544	0.858	.038	6	view →

Pink = unfavorable, green = favorable. all 4 lineages →

MIR653-LAML (DFS)

Kaplan–Meier survival curve for MIR653 RNA expression in LAML: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR653 in patient tissues and cancer cell lines. In patient samples, MIR653 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,667	COAD (3377)	view →
Function (RNA)	5,263	STAD (5237)	view →