MIR6515

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR6515 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,020 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR6515-associated GO terms across cancer lineages are Activation of GTPase activity, Peptidyl-L-cysteine S-palmitoylation, and Regulation of TRAIL-activated apoptotic signaling pathway. Each is linked with MIR6515 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR6515-to-partner and partner-to-MIR6515 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Activation of GTPase activity grouped by MIR6515-low versus MIR6515-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6515→partner) and Y-score (partner→MIR6515) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCActivation of GTPase activity →+0.051+0.056<.001<.00133
LAMLPeptidyl-L-cysteine S-palmitoylation →+0.055+1.019<.001<.00132
HNSCRegulation of TRAIL-activated apoptotic signaling pathway →+0.116+0.031<.001.00432
LAMLNeuroepithelial cell differentiation →+0.048+0.964<.001<.00132
HNSCAdaptive thermogenesis →+0.040+0.047<.001<.00132
HNSCNegative regulation of cell development →+0.035+0.061<.001<.00123
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,020 associations by consensus.

Activation of GTPase activity by MIR6515 expression — HNSC

Box plot of Activation of GTPase activity in MIR6515-low vs MIR6515-high samples in HNSC.

Explore this box plot interactively →

Exploration