MIR6511A3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR6511A3 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6511A3-associated genes across cancer lineages are POM121L1P, DEFB127, and RNU4-73P. Each is linked with MIR6511A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6511A3-to-partner and partner-to-MIR6511A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POM121L1P grouped by MIR6511A3-low versus MIR6511A3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6511A3→partner) and Y-score (partner→MIR6511A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPOM121L1P →+0.021+6.003<.001.00231
BLCADEFB127 →+0.087+4.788<.001.00631
BLCARNU4-73P →+0.278+4.685<.001.00731
SKCMMIR651 →+0.268+7.816<.001.00831
SKCMMIR767 →+0.368+7.816<.001.00831
UCECRNA5SP393 →+0.681+5.351<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

POM121L1P by MIR6511A3 expression — COAD

Box plot of POM121L1P in MIR6511A3-low vs MIR6511A3-high samples in COAD.

Explore this box plot interactively →

Exploration