MIR6511A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR6511A2 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6511A2-associated genes across cancer lineages are RNA5SP405, RNA5SP260, and RNA5SP234. Each is linked with MIR6511A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6511A2-to-partner and partner-to-MIR6511A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP405 grouped by MIR6511A2-low versus MIR6511A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6511A2→partner) and Y-score (partner→MIR6511A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP405 →+0.521+4.582<.001.00531
UCECRNA5SP260 →+1.069+3.688<.001.00731
UCECRNA5SP234 →+0.504+4.877<.001.00331
UCECRNU1-115P →+0.217+5.049<.001.00231
UCECSNORD116-17 →+0.592+4.358<.001.00131
UCECRPL10AP3 →+0.272+3.683.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

RNA5SP405 by MIR6511A2 expression — UCEC

Box plot of RNA5SP405 in MIR6511A2-low vs MIR6511A2-high samples in UCEC.

Explore this box plot interactively →

Exploration