Across TCGA pan-cancer cohorts, MIR651 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR651 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MIR651 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR651 expression acts as an unfavorable survival marker.

BLCA, LUSC, and CESC are the cancer types where MIR651 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.171	0.687	<.001	90	view →
LUSC	OS	Tertile	II,III,IV	0.031	0.743	<.001	72	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	42	view →
COAD	OS	Tertile	II,III,IV	0.183	0.788	.007	27	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
LUAD	DFS	Tertile	II,III,IV	0.178	0.721	.008	18	view →
KIRC	OS	Tertile	II,III,IV	0.339	0.813	.003	18	view →
GBM	OS	Tertile	All	0.075	0.413	.003	18	view →
BRCA	DFS	Tertile	All	0.735	0.904	.026	12	view →
HNSC	DFS	Tertile	III,IV	0.170	0.610	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration

Same gene, other analysis: MIR651 tumor-vs-normal RNA expression · all MIR651 data types