Across TCGA pan-cancer cohorts, MIR649 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR649’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR649 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR649 is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.

BRCA and PRAD are the cancer types where MIR649 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR649 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	−0.095	.022	4	view →
PRAD	All	All	−0.141	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR649 RNA expression & survival · all MIR649 data types