Across TCGA pan-cancer cohorts, MIR648 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR648’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR648 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR648 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

BRCA, KIRP, and KIRC are the cancer types where MIR648 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR648 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.161	.020	2	view →
KIRP	All	All	−0.155	.026	2	view →
KIRC	All	II,III,IV	−0.106	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR648 RNA expression & survival · all MIR648 data types