Q-omics provides the consensus-scored MIR641 profile across patient tissues and cancer cell-line models. MIR641 expression is associated with patient survival in 26 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, MIR641 is differentially expressed in 5, with the highest sampling consensus in THCA. Additionally, MIR641 RNA expression shows 18,022 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRP, THCA, and THYM as cancer lineages where MIR641 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR641 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR641 survival associations across molecular data types. MIR641 RNA expression shows survival associations in the most cancer types (26). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR641 RNA expression–survival associations across cancer types. High MIR641 expression shows unfavorable associations in ACC and ESCA, but favorable associations in KIRP, HNSC, READ and THYM. The KIRP Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify KIRP as the clearest survival context for MIR641 RNA expression.
This table summarizes MIR641 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR641. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR641 shows lower tumor expression in THCA and BRCA and higher tumor expression in COAD, PAAD and LIHC. The THCA box plot shows higher MIR641 RNA expression in normal versus tumor tissue (log2 FC = −0.923, t-test p < 0.001).
This table shows molecular features associated with MIR641 in patient tissues and cancer cell lines. In patient samples, MIR641 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.