Across TCGA pan-cancer cohorts, MIR623 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR623’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR623 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR623 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, COAD, and STAD are the cancer types where MIR623 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR623 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.336	.003	4	view →
COAD	Female	IV	+1.250	.001	1	view →
STAD	All	IV	+0.713	.003	1	view →
LUAD	Male	All	+0.481	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR623 RNA expression & survival · all MIR623 data types