MIR6127

Across TCGA pan-cancer cohorts, MIR6127 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MIR6127 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR6127 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR6127 expression acts as an unfavorable survival marker, although some lineages such as TGCT show a favorable association.

UCEC, SKCM, and KICH are the cancer types where MIR6127 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	0.402	0.841	<.001	96	view →
SKCM	OS	Tertile	All	0.714	0.881	.001	57	view →
KICH	DFS	Tertile	III,IV	0.025	0.773	<.001	54	view →
THYM	OS	Tertile	All	0.549	0.974	<.001	54	view →
OV	DFS	Tertile	All	0.253	0.542	.014	54	view →
LUSC	OS	Tertile	II,III,IV	0.054	0.780	<.001	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
KIRC	DFS	Tertile	All	0.639	0.813	.005	24	view →
TGCT	DFS	Tertile	All	1.000	0.622	.010	18	view →
LIHC	OS	Tertile	All	0.418	0.787	.017	12	view →
PCPG	DFS	Tertile	All	0.535	0.935	.048	9	view →
STAD	OS	Tertile	II,III,IV	0.237	0.709	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MIR6127–UCEC (OS)

Open the UCEC breakdown →