Across TCGA pan-cancer cohorts, MIR591 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR591’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR591 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR591 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

STAD and LUAD are the cancer types where MIR591 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR591 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Female	III,IV	−0.980	.003	1	view →
LUAD	All	All	+0.293	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR591 RNA expression & survival · all MIR591 data types