Across TCGA patient cohorts, MIR590 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,871 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR590-associated proteins across cancer lineages are PUS7, SF3B1_T426, and SP100_S410. Each is linked with MIR590 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR590-to-partner and partner-to-MIR590 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR590→partner) and Y-score (partner→MIR590) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUS7 →	+0.404	+0.507	<.001	<.001	3	4
COAD	SF3B1_T426 →	+0.437	+0.942	<.001	<.001	3	4
OV	SP100_S410 →	-1.017	-1.366	<.001	<.001	3	4
COAD	PTPN12_S435 →	+0.445	+0.747	<.001	<.001	3	3
LSCC	SCAF1_S874 →	+0.439	+0.543	<.001	<.001	3	3
BRCA	SLC39A14 →	-0.509	-0.715	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,871 associations by consensus.

Exploration

MIR590 survival (RNA) · tumor vs normal (RNA) · all MIR590 data types