Across TCGA patient cohorts, MIR587 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR587-associated genes across cancer lineages are AK4P6, OR7E145P, and COX5BP3. Each is linked with MIR587 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR587-to-partner and partner-to-MIR587 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR587→partner) and Y-score (partner→MIR587) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	AK4P6 →	+0.066	+3.979	<.001	.003	3	1
SKCM	OR7E145P →	+0.140	+3.947	<.001	.001	3	1
SKCM	COX5BP3 →	+0.130	+3.287	.003	.008	3	1
SKCM	FAM197Y6 →	+0.053	+5.219	<.001	.002	3	1
SKCM	LINC02066 →	+1.132	+3.906	<.001	.004	3	1
SKCM	SNRPCP16 →	+0.362	+3.829	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

MIR587 survival (RNA) · tumor vs normal (RNA) · all MIR587 data types