Q-omics provides the consensus-scored MIR583 profile across patient tissues and cancer cell-line models. MIR583 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MIR583 is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, MIR583 RNA expression shows 7,838 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight ACC, and BRCA as cancer lineages where MIR583 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR583 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR583 survival associations across molecular data types. MIR583 RNA expression shows survival associations in the most cancer types (12), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR583 RNA expression–survival associations across cancer types. High MIR583 expression shows unfavorable associations in ACC, KICH, KIRC, BRCA, OV and MESO. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for MIR583 RNA expression.
This table summarizes MIR583 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR583. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR583 shows higher tumor expression in BRCA. The BRCA box plot shows higher MIR583 RNA expression in tumor versus normal tissue (log2 FC = +0.181, t-test p = .042).
This table shows molecular features associated with MIR583 in patient tissues and cancer cell lines. In patient samples, MIR583 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.
