Across TCGA pan-cancer cohorts, MIR578 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR578’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR578 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR578 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

LUAD, THCA, and KICH are the cancer types where MIR578 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR578 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.219	.039	2	view →
THCA	All	All	−0.215	.040	1	view →
KICH	All	All	−0.168	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR578 RNA expression & survival · all MIR578 data types