Across TCGA pan-cancer cohorts, MIR574 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR574’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR574 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR574 is over-expressed in tumor, although a few such as LUSC and LIHC show the opposite, repressed pattern.
BRCA, LUAD, and KIRP are the cancer types where MIR574 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR574 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.