MIR5700

Across TCGA pan-cancer cohorts, MIR5700 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR5700’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR5700 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5700 is over-expressed in tumor, although a few such as BRCA and PAAD show the opposite, repressed pattern.

HNSC, BRCA, and PAAD are the cancer types where MIR5700 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5700 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.230	.002	6	view →
BRCA	All	II,III,IV	−0.160	.001	4	view →
PAAD	Female	All	−0.995	.032	2	view →
UCEC	All	All	+0.263	.039	2	view →
LUAD	All	All	−0.114	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR5700–HNSC

Open the HNSC breakdown →