Across TCGA pan-cancer cohorts, MIR5692A1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR5692A1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR5692A1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5692A1 is over-expressed in tumor.
KIRC, ESCA, and STAD are the cancer types where MIR5692A1 tumor–normal differential expression is most reproducible.