MIR5690

Across TCGA pan-cancer cohorts, MIR5690 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR5690’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR5690 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5690 is over-expressed in tumor, although a few such as CHOL and BRCA show the opposite, repressed pattern.

KIRC, CHOL, and BRCA are the cancer types where MIR5690 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5690 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.496	.001	8	view →
CHOL	All	II,III,IV	−0.950	.005	2	view →
BRCA	All	III,IV	−0.486	.040	2	view →
UCEC	All	All	−0.414	.015	2	view →
LUSC	All	All	−0.360	.009	2	view →
LUAD	All	III,IV	−0.634	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MIR5690–KIRC

Open the KIRC breakdown →