MIR5684

Across TCGA pan-cancer cohorts, MIR5684 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MIR5684’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR5684 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5684 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

KIRC, COAD, and BLCA are the cancer types where MIR5684 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5684 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.181	.010	5	view →
COAD	All	II,III,IV	+0.218	.012	3	view →
BLCA	All	All	−0.450	.041	2	view →
THCA	All	All	−0.396	.002	2	view →
UCEC	All	All	−0.373	.031	2	view →
STAD	All	II,III,IV	+0.295	.003	2	view →
KIRP	All	All	−0.260	.013	2	view →
LUAD	Female	All	−0.237	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MIR5684–KIRC

Open the KIRC breakdown →