MIR5588

Across TCGA patient cohorts, MIR5588 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,318 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR5588-associated GO terms across cancer lineages are DNA replication, Regulation of DNA repair, and Telomere maintenance. Each is linked with MIR5588 in more than 11 cancer types. Because this analysis shows association rather than direction, both MIR5588-to-partner and partner-to-MIR5588 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by MIR5588-low versus MIR5588-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR5588→partner) and Y-score (partner→MIR5588) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	DNA replication →	+0.064	+0.355	<.001	<.001	3	12
ESCA	Regulation of DNA repair →	+0.055	+0.357	<.001	<.001	3	12
ESCA	Telomere maintenance →	+0.061	+0.391	<.001	<.001	3	12
ESCA	DNA double-strand break processing →	+0.051	+0.445	<.001	<.001	3	12
STAD	Peptidyl-lysine modification →	+0.053	+0.315	<.001	<.001	3	12
STAD	DNA strand elongation →	+0.059	+0.356	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,318 associations by consensus.

DNA replication by MIR5588 expression — ESCA

Explore this box plot interactively →