MIR5583-1

Across TCGA pan-cancer cohorts, MIR5583-1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MIR5583-1 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher MIR5583-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR5583-1 expression acts as an unfavorable survival marker, although some lineages such as CESC and LUSC show a favorable association.

TGCT, KIRC, and SKCM are the cancer types where MIR5583-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	90	view →
KIRC	OS	Tertile	II,III,IV	0.179	0.558	.007	48	view →
SKCM	DFS	Tertile	All	0.015	0.758	<.001	45	view →
THCA	DFS	Tertile	All	0.062	0.811	<.001	45	view →
BLCA	DFS	Tertile	All	0.336	0.631	.003	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
READ	DFS	Tertile	All	0.179	0.701	.022	27	view →
LIHC	OS	Tertile	All	0.169	0.669	.032	18	view →
UCEC	DFS	Tertile	III,IV	0.091	0.581	.030	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	15	view →
CESC	DFS	Tertile	III,IV	1.000	0.289	.042	12	view →
LGG	DFS	Tertile	All	0.170	0.731	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MIR5583-1–TGCT (OS)

Open the TGCT breakdown →