Across TCGA pan-cancer cohorts, MIR557 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR557 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher MIR557 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR557 expression acts as an unfavorable survival marker.

SKCM and LUAD are the cancer types where MIR557 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.138	0.871	<.001	29	view →
LUAD	DFS	Median	All	0.098	0.768	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR557 tumor-vs-normal RNA expression · all MIR557 data types