Across TCGA pan-cancer cohorts, MIR550A1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR550A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR550A1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR550A1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and BRCA are the cancer types where MIR550A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR550A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.210	.001	5	view →
KICH	All	II,III,IV	−0.451	.017	3	view →
BRCA	All	III,IV	−0.298	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR550A1 RNA expression & survival · all MIR550A1 data types