Across TCGA pan-cancer cohorts, MIR548P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR548P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR548P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR548P is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.
KIRC, COAD, and LUSC are the cancer types where MIR548P tumor–normal differential expression is most reproducible.