Across TCGA pan-cancer cohorts, MIR548K RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR548K’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR548K RNA is repressed in tumor relative to normal tissue. In most cancer types MIR548K is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC, UCEC, and LIHC are the cancer types where MIR548K tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548K RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	III,IV	−0.685	.002	3	view →
UCEC	All	IV	+1.200	.008	2	view →
LIHC	Female	All	+0.091	.039	2	view →
STAD	All	All	+0.318	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR548K RNA expression & survival · all MIR548K data types