Across TCGA pan-cancer cohorts, MIR548I1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR548I1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR548I1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR548I1 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, COAD, and BRCA are the cancer types where MIR548I1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548I1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.222	.004	3	view →
COAD	All	All	−0.210	.004	3	view →
BRCA	All	All	−0.139	.017	2	view →
LUAD	All	III,IV	−0.188	.042	1	view →
KICH	Female	All	−0.186	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MIR548I1 RNA expression & survival · all MIR548I1 data types