MIR548AO

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR548AO RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR548AO’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR548AO RNA is repressed in tumor relative to normal tissue. In most cancer types MIR548AO is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, BRCA, and KIRP are the cancer types where MIR548AO tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548AO RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCAllAll−0.140<.00110view →
BRCAFemaleAll−0.395<.0016view →
KIRPAllAll−0.162.0082view →
KICHAllAll−0.123.0401view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR548AO–KIRC

Tumor-vs-normal expression box plot for MIR548AO RNA in KIRC.

Open the KIRC breakdown →

Exploration