MIR548AE2

Across TCGA patient cohorts, MIR548AE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,371 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR548AE2-associated GO terms across cancer lineages are Antigen processing and presentation of peptide antigen via MHC class I, Regulation of Rab protein signal transduction, and Regulation of hyaluronan biosynthetic process. Each is linked with MIR548AE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR548AE2-to-partner and partner-to-MIR548AE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of peptide antigen via MHC class I grouped by MIR548AE2-low versus MIR548AE2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR548AE2→partner) and Y-score (partner→MIR548AE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Antigen processing and presentation of peptide antigen via MHC class I →	+0.090	+0.126	<.001	.006	3	2
STAD	Regulation of Rab protein signal transduction →	+0.106	+0.135	<.001	.003	3	2
ESCA	Regulation of hyaluronan biosynthetic process →	+0.077	+0.141	.003	.003	3	2
LAML	Response to ozone →	-0.053	-0.629	.007	.001	3	1
LAML	Regulation of glucose transmembrane transport →	-0.028	-0.756	<.001	<.001	3	1
LAML	miRNA-mediated gene silencing by inhibition of translation →	+0.026	+0.692	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,371 associations by consensus.

Antigen processing and presentation of peptide antigen via MHC class I by MIR548AE2 expression — STAD

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