Across TCGA pan-cancer cohorts, MIR548A3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR548A3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR548A3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR548A3 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, BRCA, and KIRC are the cancer types where MIR548A3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548A3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.237	.003	8	view →
BRCA	All	IV	+0.655	<.001	4	view →
KIRC	All	All	−0.159	.008	4	view →
LUSC	Male	All	+0.339	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR548A3 RNA expression & survival · all MIR548A3 data types