Across TCGA pan-cancer cohorts, MIR532 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MIR532’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where MIR532 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR532 is over-expressed in tumor.
ESCA are the cancer types where MIR532 tumor–normal differential expression is most reproducible.