Across TCGA pan-cancer cohorts, MIR519A1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MIR519A1 data layer compared with 2 for mutation status.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher MIR519A1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR519A1 expression acts as an unfavorable survival marker.
PAAD, SARC, and SKCM are the cancer types where MIR519A1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.