Across TCGA pan-cancer cohorts, MIR519A1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR519A1 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher MIR519A1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR519A1 expression acts as an unfavorable survival marker.

LGG and CESC are the cancer types where MIR519A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.172	0.845	<.001	9	view →
CESC	OS	Median	All	0.287	0.798	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR519A1 tumor-vs-normal RNA expression · all MIR519A1 data types