MIR5195

Across TCGA pan-cancer cohorts, MIR5195 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR5195 data layer compared with 2 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MIR5195 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR5195 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

THCA, PAAD, and LUAD are the cancer types where MIR5195 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	IV	0.815	1.000	<.001	44	view →
PAAD	DFS	Tertile	II,III,IV	0.623	0.354	.009	43	view →
LUAD	DFS	Quartile	All	0.843	0.698	<.001	36	view →
SKCM	DFS	Tertile	All	0.734	0.579	.010	34	view →
SARC	DFS	Tertile	All	0.833	0.589	.010	27	view →
ESCA	DFS	Quartile	II,III,IV	0.702	0.419	.004	21	view →
KIRC	DFS	Quartile	IV	0.778	0.488	.010	18	view →
READ	DFS	Median	IV	0.179	0.936	.010	17	view →
TGCT	DFS	Quartile	All	0.932	0.719	.016	14	view →
BRCA	OS	Median	All	0.608	0.540	.017	11	view →
OV	DFS	Quartile	II,III,IV	0.218	0.149	.032	10	view →
HNSC	DFS	Quartile	III,IV	0.484	0.277	.026	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR5195–THCA (OS)

Open the THCA breakdown →