MIR5188

Across TCGA pan-cancer cohorts, MIR5188 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MIR5188’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR5188 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5188 is over-expressed in tumor, although a few such as THCA and HNSC show the opposite, repressed pattern.

KIRC, KIRP, and UCEC are the cancer types where MIR5188 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5188 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.506	<.001	10	view →
KIRP	All	All	+0.358	.005	5	view →
UCEC	All	All	+0.409	.011	4	view →
LUSC	All	All	+0.366	<.001	4	view →
LIHC	Male	All	+0.340	.001	4	view →
BRCA	Female	II,III,IV	+0.200	.010	4	view →
THCA	All	All	−0.408	<.001	3	view →
HNSC	All	All	−0.624	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MIR5188–KIRC

Open the KIRC breakdown →