Across TCGA pan-cancer cohorts, MIR517A RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated MIR517A data layer compared with 2 for mutation status.
The strongest signal is observed in brain lower grade glioma (LGG), where higher MIR517A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR517A expression acts as an unfavorable survival marker.
LGG, PCPG, and STAD are the cancer types where MIR517A RNA most reproducibly stratifies survival.