Across TCGA pan-cancer cohorts, MIR516B1 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated MIR516B1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR516B1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR516B1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, ESCA, and KIRC are the cancer types where MIR516B1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.005	0.784	<.001	108	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	18	view →
SKCM	DFS	Tertile	II,III,IV	1.000	0.561	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR516B1 tumor-vs-normal RNA expression · all MIR516B1 data types