MIR515-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR515-2 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated MIR515-2 data layer compared with 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR515-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR515-2 expression acts as an unfavorable survival marker.

UCEC, TGCT, and STAD are the cancer types where MIR515-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileII,III,IV0.2010.771<.00190view →
TGCTOSTertileIII,IV0.5011.000.01454view →
STADOSTertileIII,IV0.0520.629<.00154view →
SKCMDFSTertileIII,IV0.1300.601.00336view →
LIHCOSTertileAll0.4490.778.03227view →
THCADFSTertileAll0.6000.915.02518view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration